Skin boosters represent new-age technology and are frequently used to improve skin quality, texture and increase hydration. They contain non-cross-linked hyaluronic acid (in contrast with fillers, which contain cross-linked hyaluronic acid). This is crucial for skin hydration, which decreases naturally with age. Certain other activities may be included along with hyaluronic acid, such as skin boosters that contain glutathione as well. Glutathione is a master antioxidant, which helps to boost skin radiance and give a long-lasting glow. There are also skin boosters that contain polynucleotides which are great for skin rejuvenation. They promote cell turnover and proliferation and provide a youthful boost. Stem cell-based skin boosters are also gaining popularity. These skin boosters are injected strategically on the face and neck. Correct technique and proper knowledge of anatomy are absolutely essential to get the best results, with minimal complications. The procedure is virtually painless after the application of topical anesthesia, with minimal downtime. There can be swelling, redness, and bruising for a few days after the procedure, which is why a procedure should be planned a few days before an upcoming event. Skin boosters can improve the appearance of not only the face and neck but also the hands which can tend to look old and wrinkled. Usually the results last for about 6-12 months, depending on the product used and the patient’s metabolism.